Recode v. 2.0 / Database of translational recoding events.

 

Details for "r200022"

Accession numberr200022 [export]
Locus namedio2
Recode1 namedio2_s_euk_drer
Descriptioniodothyronine deiodinase
Recode statusValidated

Organism

Genomic classEukaryota (Chromosome)
OrganismDanio rerio [details]

Sequence

GenBank IDsNM_212789.2,BC059608.1,AY221260.1
SequencemRNA of 2183 nucleotides [sequence]
OrganisationSECIS (1) [see structure]

Recoding event

Event typeSelenocysteine (positions: 645, 1041)
Descriptionselenocysteine incorporation.
CTCTGGTTAA TTGTAATGCG GAAAGGAGGG GGGCACTTGG CACCGGCGCT CCTCTGTGCG TAAAGACGCC TGATGCTTGG CGAGACGCAG ATTCGGGCTC ACCGCGCGCT AACGCCCACA TCCTCAAGCC GACTCTGCTT TCTTTAGGTG AATGAAAGTT TGCTAGGAGG GGGACGGCAG AAGAAATGAT ATCTGACCAG GATGAGTCGG AAAGGTGAAG TTAAATAAGC AAAAGTGCGC GTCAACCACC TGTTATAAAT CAGCGCGAAA TGGGCTTGCT TAGTGTGGAC CTCCTGGTAA CTTTGCAGAT TTTGCCTGGC TTCTTCTCCA ACTGCCTGTT TTTCGTGCTG TATGACTCGA TAGTGCTGGT TAAGCGTGTG GTGTCACTCC TGAGCTGCTC GGGCTCCACG GGTGAGTGGC AGCGCATGTT AACCACAGCC GGCGTGCGCT CCATATGGAA CAGCTTTCTT CTGGATGCCT ACAAACAGGT GAAATTGGGC GAAGCTGCTC CAAACTCTAA GGTGGTGAAA GTCACTGGCA TCAATAGATG CTGGAGCATC AGCGGTAAGA CCCACAACCA GTGCCACCTG CTGGACTTTG AGTCTCCTGA TCGCCCGTTA GTGGTCAACT TCGGTTCGGC CACTTGACCC CCCTTTATAA GCCAGCTGCC GGTCTTCCGG CGGATGGTGG AGGAATTTTC AGATGTGGCA GATTTCCTGC TGGTCTACAT CGATGAGGCT CACCCTTCAG ACGGCTGGGT GGGTCCTCCC ATGGAGAACT TTTCGTTTGA AGTGAGGAAA CACCGAAATC TGGAGGAGAG GATGTTTGCC GCCAGGACAC TTCTGGAGCA TTTCTCCTTG CCTCCTCAGT GCCAGTTGGT GGCCGATTGC ATGGACAATA ATGCCAACAT AGCCTATGGT GTGTCCTACG AGAGGGTCTG CATCGTGCAG AAGAATAAAA TCGCTTACCT TGGGGGTAAG GGTCCATTTT TTTACAACCT TAAAGATGTT CGGAGATGGC TGGAGAAGTG CTACGGAAAG TGATAATTTC TCGGAGAAAA TAAAGAGGTC AAAATAGCCT TTTCTGTGAA TGTTAGAAGA TTTTATTTTT GTATAATGGA GAGAATCGAG GGAAAGGTGC TTTTGGGACT GTTTAACGGT GGCTCCAGTG GAAACACTTG GGCTGGGCTC CAAGTCATTT TTTTTGAATA TTTTTTTTAA ATGATAAACA GGTGTCCTAC ATTCCTAACC ACTTTAAAAA GAAAGAATGA AATGAATATA GACACTAAAT ACTGACCTTG TGGTTTGCAC TTCAATTTTG AGATTACATT GTTGCCAGCA AAATGATTTG TAGATGCACT ATTAATAACT TGTTCCTTTT GCAATTAATG TAGAGTTAAA AGTGTGCAAT ATTTTTATGC GACATAACAT ATATTGCTTA CAAAAGAAAA CCAAATTGCT GAAGAGAAGA GAAAGCACAA GTTCCCAGCT TTTATATGAA AAGAGAATAA TTTATTTTTA TTGACATGTT TATTTTTAAT ATGTGGCCTG TTTATGCACT TGTAATGCTT TCCCTCGCCC TGACAACTGA CAATCATTCA CATTCCATGT ATCAGCTTTT ACATTCGCAC CAGTAACAAA AGCATTATCG GCATCCAATA ACCACAGCTA CTAATAATGC AAGTCGTTTG ACCTGTATTG TACTCTTACT GCTCTTAATA AGCTGGACAA ATGGAGGGAA AATTCTCCCA GCAGCCACAG CCACCGAACT TAACTCGGAC ACTTGGCTTG ACTGCTGTGT ACAGGAAAGC TGACGGAAAG TTCTTTTACT CCTGAATGTT AGAGAAATGT TTTTGAATGT TGTTGATGGT GACTTTAACG CATAGGCAGT CGCTCATTTG GTTCAATACG GTGTTGGTGT GCACATGAAA ATCACAGATG AAATGGTCCC CTGTCCTGTC TGTGGTTGGA TGAGAGACCA CACCTCTCCG TCCTGATCCA AATAGGCATG ACTGCTAACA TGCGGAAACA ATCACTCTGA ATCTGAATCA CTCTGAAGGC TTTGAGTTTT GCTTCACAGA ACAGTTCTCA TGTACTACAA CTGTCCTCGT CCTTTTAATG AGAAAAAGGC AAGACAAAAT AAAGTTGAAC TGCTGCTGAC TATGAAAAAA AAAAAAAAAA AAA

Product

Productdio2
Descriptiontype II iodothyronine deiodinase (DIO2); catalyzes the 5'-deiodination of thyroxine (T4, prohormone) to form 3,5,3'-triiodothyronine (T3, active hormone)
Modifications645..647,aa:Sec|1041..1043,aa:Sec
MGLLSVDLLV TLQILPGFFS NCLFFVLYDS IVLVKRVVSL LSCSGSTGEW QRMLTTAGVR SIWNSFLLDA YKQVKLGEAA PNSKVVKVTG INRCWSISGK THNQCHLLDF ESPDRPLVVN FGSATUPPFI SQLPVFRRMV EEFSDVADFL LVYIDEAHPS DGWVGPPMEN FSFEVRKHRN LEERMFAART LLEHFSLPPQ CQLVADCMDN NANIAYGVSY ERVCIVQKNK IAYLGGKGPF FYNLKDVRRW LEKCYGKU

Publication