Recode v. 2.0 / Database of translational recoding events.

 

Details for "r200041"

Accession numberr200041 [export]
Locus nameselP
Recode1 nameselP_s_euk_rnor
Descriptionselenoprotein P
Recode statusValidated

Organism

Genomic classEukaryota (Chromosome)
OrganismRattus norvegicus [details]

Sequence

GenBank IDsM63574.1,NM_019192.1,D25221.1
SequencemRNA of 2794 nucleotides [sequence]
OrganisationSECIS structure (2)

Recoding event

Event typeSelenocysteine (positions: 209, 824, 878, 1001, 1037, 1103, 1145, 1151, 1172, 1178)
DescriptionSelenocysteine incorporation. mRNA contains 10 UGA codons, each of which can be translated as selenocysteine; efficiency of Sec incorporation at each UGA in selP mRNA appears to be different which results in multiple product forms; in particular, the second in frame UGA dictates significant termination giving rise to selenoprotein which may have a separate function. 3'UTR contains 2 SECIS elements.
AAGCTAGTCT GAAGGGGTTG CGAAAACCCC AGCAATGTGG AGAAGCCTAG GGCTTGCCCT GGCTCTCTGT CTCCTCCCCT ATGGAGGAGC AGAGAGCCAA GGCCAAAGCC CTGCTTGTAA GCAAGCTCCA CCCTGGAACA TAGGAGATCA AAATCCAATG CTAAACTCCG AGGGCACAGT GACAGTGGTT GCTCTTCTTC AAGCCAGCTG ATACCTGTGC CTTCTGCAGG CATCCAGATT GGAAGACCTG CGAATAAAAC TAGAGAACCA AGGATATTTT AACATCTCCT ATATTGTTGT TAATCATCAA GGATCTCCTT CCCAATTAAA ACATGCACAT CTTAAAAAGC AGGTGTCAGA TCACATTGCT GTTTACAGAC AAGATGAACA TCAAACAGAT GTCTGGACAC TCTTAAATGG AAACAAAGAT GACTTCCTCA TATATGACAG ATGTGGCCGT CTTGTGTATC ACCTTGGTTT GCCCTACTCC TTCCTCACTT TCCCGTATGT TGAAGAAGCC ATCAAGATCG CTTACTGTGA GAAGAGGTGT GGAAACTGCT CTTTCACGAG TCTTGAAGAT GAAGCCTTCT GTAAAAACGT GTCCTCGGCT ACTGCAAGTA AAACCACAGA GCCCTCAGAG GAGCATAACC ACCACAAGCA CCATGACAAA CATGGGCATG AGCATCTTGG GAGCAGTAAG CCTTCAGAGA ATCAGCAACC AGGGGCATTA GATGTTGAGA CAAGTCTTCC TCCTTCAGGC TTGCACCACC ACCACCACCA CCATAAGCAC AAGGGCCAGC ACAGGCAGGG TCACTTAGAG AGCTGAGACA TGGGGGCAAG TGAAGGCTTG CAACTTTCAC TTGCCCAGAG GAAGCTCTGA CGAAGGGGAT GCATAAACCA GCTCCTGTGT AAGTTATCTG AGGAGTCTGG GGCAGCTACC AGTAGCTGCT GCTGCCACTG CCGACACCTC ATATTTGAGA AGTCAGGATC TGCAATCACT TGACAGTGTG CCGAAAACCT CCCATCCTTG TGTAGCTGAC AGGGGCTTTT CGCGGAGGAG AAAGTCATTG AATCCTGTCA ATGTAGATCA CCTCCAGCTG CCTGACACAG TCAGCATGTA AGCCCCACAG AAGCCAGCCC CAACTGAAGC TGAAATAATA AGACCAAGAA GTGAAAATGA AATTTGAACT AAATATTTAA AATAAAGCGT ACTCTCCCCA ACTCCATCTA AAGACACAAT TTCATTTCTA GAATGTTTCC AATCCATTTA ATTAATTAGT GAAGTAAAAG TAGTTGAAAT TGGATTTGTG CAAACATGGA GAAATCTACC ACATTGGCTT CTAAAATTTA AAATTTTTAT GCCACAAACC ATTTCATCCA AATCAGATTT GTACCGTGGG GCAACTGAAA AGTGATTGCG GCCATTGGTT AATATGTCTT CCTTTTTCTT TCTCCAGTGT TCTAGTTACA TTGATGAGAA CAGAAACATA AACTATGACC TAGGGGTTTC TGTTGGATAG CTCGTAATTA AGAACGGAGA AAGAACAACA AAGACATATT TTCCAGTTTT TTTTCTTTAC TTAAAACTTT CAAAACAATA GAAACTTTGT CTTTCTAATC TTATACTTTA AACCGATTAA ATCTTTAACA GACTACATTT TAAATATCTA CTTATCTTTT TTATCTCTAA GACTCCTAGT TTGAGTTTCA CTACATATAT CTGTGAATCT TGTTTTTTCA TCTAATGCTG TATCAGTCTT CTGAGTTGTG AGTGACTGTC TTGAAAGAGT AATGGAAGAA AAGATGGTGT TAATCTGCAT AGTGCTTAAG ACAGTATTTC CATAATCAAT GACGGTTTAA TAGAGAAACT GAGTCCTATG AACCTGAACT CCTTTATGGC TAATACAATT AAGCAAGAAT GGAGAATAGA ATTGATTGGC TACAGTACAG ATTATCAAAA ATAAATGCAA CTTAAAAAGC TGGAAAGTGT GTGTCTTTAT TGTTCAGCTC ACATTGAAAG TAGAAGTGCA TCTTTAGAGC CTTAAAGAAA ACTAGGTAAG TTGTTGCTAA TACACTAAGT GCCCTGCTCA AAACCGCCTC CGAGTGAGGG CTGTCTTTGG AGGCCGCGAG CTGCTCTAGG TCTCGGATAG TGTTCTGGAG ACTTGCAATT TCTTGTTCTT TTCCTCCTGA AGAGCTGAAG CTTCTAAATG AAGCAGAAAA AAAACTTTGT CATAGCAACT TAGAAGTAAG GTTAAGTATA ATGAACTACA AAGTAGCAAT CATAACATTT GTACTTTAAA AACTATCCTA TGGACTGGAA GGCCTGTAGC TTCATTTTTG GTGTGCTTTA AAGAGAAAGT CTAGTATAAG GCTACAAAAA TAATTTAATA TACTTAAAAC AAATATGGTT TGCCCTGGAG TTATCGGTAT TTTGATGCTA ATTTCACTGC CCCAAGGACA GCTGCTTAGT CACATACTCA GGAATCAGTG ACTTCACCAG AACCTTCTTC CCACTGAATT TGTAAAATAC AGGTGAGGGG CAGGTATAGG ATAGAAGGAG GCCTGTCATT GGAGGAGAAG GAAGGATGGG CGGGAGAGAA GTTTGAAGGA AGAGGAGAAG ACTGGAATGG AAAAGAGGAA GAGACAGGAG GGAGAGAGAG AGAAGCCATG GCAGGAGACA TTAAGATTCT GTTCTGTGTA TTTACAGGTT GCTATTAATA TGTTCTTAAG GGATGGATGG TACTGGGCTT TGTATGTTTA GGTGGGCAAT TATATCTTAT CAATTGGATC TAAA

Product

ProductselP
Descriptionselenoprotein P, antioxidant? selenium storage (or transport)?
Modifications209..211,aa:Sec|824..826,aa:Sec|878..880,aa:Sec|1001..1003,aa:Sec|1037..1039,aa:Sec|1103..1105,aa:Sec|1145..1147,aa:Sec|1151..1153,aa:Sec|1172..1174,aa:Sec|1178..1180,aa:Sec
MWRSLGLALA LCLLPYGGAE SQGQSPACKQ APPWNIGDQN PMLNSEGTVT VVALLQASUY LCLLQASRLE DLRIKLENQG YFNISYIVVN HQGSPSQLKH AHLKKQVSDH IAVYRQDEHQ TDVWTLLNGN KDDFLIYDRC GRLVYHLGLP YSFLTFPYVE EAIKIAYCEK RCGNCSFTSL EDEAFCKNVS SATASKTTEP SEEHNHHKHH DKHGHEHLGS SKPSENQQPG ALDVETSLPP SGLHHHHHHH KHKGQHRQGH LESUDMGASE GLQLSLAQRK LURRGCINQL LCKLSEESGA ATSSCCCHCR HLIFEKSGSA ITUQCAENLP SLCSUQGLFA EEKVIESCQC RSPPAAUHSQ HVSPTEASPN USUNNKTKKU KUNLN

Publications