Recode v. 2.0 / Database of translational recoding events.

 

Details for "r200319"

Accession numberr200319 [export]
Locus nameselP
Recode1 nameselP_s_euk_btau
Descriptionselenoprotein P
Recode statusReviewed

Organism

Genomic classEukaryota (Chromosome)
OrganismBos taurus [details]

Sequence

GenBank IDsAB032826.1,D88033.1
SequencemRNA of 1914 nucleotides [sequence]
OrganisationSECIS structure (2)

Recoding event

Event typeSelenocysteine (positions: 175, 841, 871, 964, 1000, 1039, 1045, 1066, 1114, 1120, 1141, 1147)
DescriptionSelenocysteine incorporation. mRNA contains 12 UGA codons, each of which can be translated as selenocysteine; efficiency of Sec incorporation at each UGA in selP mRNA appears to be different which results in multiple product forms; in particular, the second in frame UGA dictates significant termination giving rise to selenoprotein which may have a separate function. 3'UTR contains 2 SECIS elements.
ATGTGGAGAG GCCTGGGGCT GGCTCTGGCT CTCTGCCTCC TCCTAACCGG AGGGACAGAG AGCCAGGGCC AAAGCTCCTA TTGTAAGCAA CCTCCACCCT GGAGCATAAA GGATCAAGAC CCTATGCTGA ACTCCTACGG TTCAGTGACT GTGGTTGCTC TTCTTCAAGC CAGCTGATAC CTGTGCATTC TGCAGGCATC TAGATTGGAG GACCTGCGAG TAAAACTGGA GAAAGAAGGA TATTCTAACA TCTCCTATGT TGTTGTTAAT CATCAAGGAA TCTCTTCTCG ATTAAAATAT GTGCATCTTA AAAATAAGGT TTCAGAACAT ATTCCTGTTT ACCAACAAGA AGAAAACCAA CCAGATGTCT GGACTCTCTT AAATGGAAAC AAAGATGACT TCCTCATATA TGACAGATGT GGCCGCCTTG TATATCATCT TGGTTTGCCT TATTCCTTCC TAACTTTCAC ATATGTAGAA GATTCCATTA AGACTGTTTA CTGTGAAGAT AAATGTGGAA ACTGCTCTCT CAAGGCACTG GAAGATGAAG ACGTCTGTAA AAATGTATTT CTGGCTACCA AGGAGAAAAC AGCTGAGGCT TCACAGCGAC ATCACCACCC CCACCCCCAT CCCCATCATG GGCATCAGCT TCATGAAAAT GCTCATCTTT CAGAGTCTCC AAAACCAGAC ACACCAGATA CCCCTGAGAA TCCCCCTCCT TCAGGTCTTC ATCACCACCA CCACAGGCAC AAGGGTCCCC AAAGACAGGG TCACTCAGAT AACTGTGATA CACCAGTAGG AAGTGAAAGT TTACAACCTT CTCTTCCACA AAAGAAGCTC TGACGAAAGA GATGCATAAA TCAGTTACTC TGACAGTTTC CCAAAGACTC AGAATCTGCT TTGAGTAGCT GCTGTTGCCA CTGTCGACAT CTGGTATTTG AAAAAACAGG GTCTGCAATC ACCTGACAGT GTACAGAAAA GCTCCCCTCT TTGTGTAGCT GACAGGGCCT TTTGGCGGAG GAGAATGTCA TTGAATCTTG ACAGTGACGT TTGCCTCCAG CTGCCTGACA GGCAGCAGGT CAGCAGCTCA ACCCCACAGA AGCCAGCACC AAGTGAAGCT GAAAAAATAA GGCCAAAATG TGAAAATGAC CTTCAAATTA AATATATGAA ATTGGATATA TTCCCCAAGT CAATCTACAC AATTGCATTT CCAGCATTTG TATAAGGTAC CTAATTAACA GTGATCCAAA AATAGGAATT GGATTTGTGC AAACATGGAG AAATTGACTT CCATAAAATT TAAGTCAAAG AAATTTTGAC CCAAACCATA TTTTTATTCA GCTGAGAGGT GGTTGCAGCG TTTGGTTAGC ATGTCTTTCT TTTTCTTTTT CCAGTATTCT ACTTGCGTTA ATGAGAACAG AAACGTAAAC TATAACCTAG GGGTTTCTGT TGGATGGTTG GCAACTAAGA ATGGAGGAAG AACAACAAAG ACATGTTCTC CACTTTCTTA TTTCTCAAAA CAATGTTATC TTCGTCTTTT TAATCTTAGG TTTTTAACAG ATTAAACCTT TAAAGCAAGA AGTGAATTCT GTCTTTTCAG ACCCAGAAAT ACACATGAAT ACTTTGCTAT GATTACATTT TAGATATTCA TTTATACTTT TCTATATCTA AGACTCATAT CTTGATTTTT ACTATCATAT ATGAATGAAG CCTTTATATC TTGTTTTTTT GCCAATCTTG AAAGATAGAT GGGAAAAGAT AAAAGAATGT TGTCTAACTC TTGATTGCTT AGAAAGTATT TCCATAGTCA ATGATGGTTC AATAGGCAAA CCAGGTCCTA TAAACCTGAA TTTTTTTTAT GGTCAATACT GTTAAGCAGA AATGTAGGCA AAAATGTGGA TGTTTAAATT CAAT

Product

ProductselP
Descriptionselenoprotein P, antioxidant? selenium storage (or transport)?
Modifications175..177,aa:Sec|841..843,aa:Sec|871..873,aa:Sec|964..966,aa:Sec|1000..1002,aa:Sec|1039..1041,aa:Sec|1045..1047,aa:Sec|1066..1068,aa:Sec|1114..1116,aa:Sec|1120..1122,aa:Sec|1141..1143,aa:Sec|1147..1149,aa:Sec
MWRGLGLALA LCLLLTGGTE SQGQSSYCKQ PPPWSIKDQD PMLNSYGSVT VVALLQASUY LCILQASRLE DLRVKLEKEG YSNISYVVVN HQGISSRLKY VHLKNKVSEH IPVYQQEENQ PDVWTLLNGN KDDFLIYDRC GRLVYHLGLP YSFLTFTYVE DSIKTVYCED KCGNCSLKAL EDEDVCKNVF LATKEKTAEA SQRHHHPHPH PHHGHQLHEN AHLSESPKPD TPDTPENPPP SGLHHHHHRH KGPQRQGHSD NCDTPVGSES LQPSLPQKKL URKRCINQLL UQFPKDSESA LSSCCCHCRH LVFEKTGSAI TUQCTEKLPS LCSUQGLLAE ENVIESUQUR LPPAAUQAAG QQLNPTEAST KUSUKNKAKM UKUPSN

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