Recode v. 2.0 / Database of translational recoding events.
Details for "r200332"
| Accession number | r200332 [export] |
| Locus name | SPS2; selD2 |
| Recode1 name | sps2_s_euk_hsap |
| Description | selenophosphate synthetase |
| Recode status | Validated |
Organism
| Genomic class | Eukaryota (Chromosome) |
| Organism | Homo sapiens [details] |
Sequence
| GenBank IDs | U43286.1 |
| Sequence | mRNA of 2253 nucleotides [sequence] |
| Organisation | SECIS structure (1)
|
Recoding event
| Event type | Selenocysteine (position: 316) |
| Description | Selenocysteine incorporation. |
GTGCATGCCG TGGGTCTGAC GGCTTGAGTA GCGCTAGGGA GAATCCCTGC AGGTAATATT TGACTTTTGC
TTCATATTAA TCTGAGTGGA AAATAAAAGG GCCCTCTTCT CCTCTCGCTT CCCTGCCGGG CAGGCGCCAT
GGCGGAAGCC TCGGCGACGG GCGCCTGCGG AGAGGCGATG GCAGCGGCGG AAGGCTCCTC GGGCCCGGCG
GGCTTGACTC TGGGCCGGAG CTTCTCGAAC TACCGGCCCT TCGAGCCCCA GGCGTTGGGC CTCAGCCCGA
GCTGGCGGCT GACGGGCTTC TCCGGCATGA AGGGCTGAGG CTGCAAGGTC CCGCAGGAGG CGCTGCTCAA
ACTCCTGGCG GGACTGACGC GGCCGGACGT GCGGCCCCCG CTGGGCCGGG GCCTGGTGGG TGGCCAGGAA
GAGGCGTCCC AGGAAGCCGG CCTGCCGGCA GGAGCGGGCC CCAGCCCCAC CTTTCCAGCC CTGGGCATCG
GGATGGACTC CTGCGTCATC CCCCTGAGGC ACGGGGGCCT GTCACTGGTG CAGACCACGG ACTTCTTTTA
CCCCTTGGTA GAAGATCCCT ACATGATGGG GCGCATAGCT TGTGCCAACG TGCTGAGTGA CCTCTACGCC
ATGGGGATTA CTGAGTGTGA CAACATGTTG ATGTTACTCA GCGTCAGCCA GAGTATGAGT GAGGAGGAAC
GCGAAAAGGT AACGCCACTC ATGGTCAAAG GCTTTCGGGA TGCGGCTGAG GAAGGAGGGA CGGCAGTGAC
CGGTGGGCAA ACGGTGGTCA ACCCTTGGAT TATAATCGGT GGAGTTGCCA CTGTAGTATG CCAACCAAAT
GAGTTCATAA TGCCGGACAG CGCCGTCGTT GGGGACGTGC TGGTGTTAAC CAAACCGTTA GGAACCCAGG
TTGCTGTCAA TGCCCACCAA TGGCTGGATA ATCCTGAAAG ATGGAATAAA GTAAAGATGG TGGTCTCCAG
AGAAGAGGTG GAGCTGGCCT ATCAGGAAGC CATGTTCAAT ATGGCTACCC TCAACAGAAC TGCTGCAGGT
TTAATGCACA CATTTAATGC CCATGCGGCC ACAGATATCA CAGGCTTTGG CATTCTAGGA CACTCCCAGA
ACCTTGCAAA ACAACAAAGA AATGAAGTGT CCTTTGTTAT TCATAATCTG CCAATAATTG CCAAGATGGC
TGCCGTCAGC AAGGCCAGTG GACGGTTTGG GCTTCTTCAA GGAACCTCAG CTGAAACCTC TGGGGGATTA
CTGATTTGTC TGCCAAGAGA ACAGGCGGCT CGCTTTTGTT CTGAAATCAA ATCCTCCAAG TACGGAGAGG
GTCACCAAGC GTGGATCGTT GGCATTGTGG AAAAGGGAAA CCGAACGGCC CGGATCATTG ACAAGCCGCG
AGTTATTGAA GTCCTGCCTC GTGGGGCCAC AGCTGCTGTT CTTGCTCCTG ACAGTTCAAA TGCCTCCTCT
GAGCCTAGCT CGTGAGATGA AAGAACAGAA GTTGTTTGGA CCTTAGAGCC ATTGTCCACA ATCACGGATG
GTTCTCAAGA GTTGATTGTA AGAAATTTCC AAAGAAGGCT GCCTGCATAG TGGTTCCGGC TGCCCTTTCT
AGGTGATTGG AATCAGCCCA TCTAAAGCAG TCTTTATATG CATTCCGAGG CCAGAGTAAC ATTTTGAACT
TTGGGGGGAT ATTTGTTCAT CACTTGGGTA GAAGAGGAGC AAAAATACTT CTGTTTTCTC TTGCCAAAGT
AAGATGAAGC TATTCCAGGT TGAGGGATTT TTCTTTGCAC GGGGTTGATT AATTTCTGCA CAGGGAGTGA
GATTATTAAA GTAACACACA CACAAAGTAA ATTGCAAAAT GAAAAAAATT AGAAGCAAAT GAGTTTTGGA
CCAATATTGT TGATAAATCT AAATTGTTAA GAGAGATCTT ATAATGCAAC ATCAAATTCT TTATTCAATT
TTACTGAAGT ACTGGCTCTT TCCTGCTCTG GACAAGAATT GAGCAACTTG TCTGATGACT GGGAAAGGAG
GACCTGCAAC CATCTGACTT GGTCTCTGTT AATGACGTCT CTCCCTCTAA ACCCCATTAA GGACTGGGAG
AGGCAGAGCA AGCCTCAGAG CCCAGGCCTC AGTGGTCATT AAGATGTTAA GTCTTTTGCG GCAGATTCCT
GGTGATTTGA TCAATAAAGA GTAATTTCTT GCTAAATAAA TAAAAGAAAC CTTGTTGAAA AACTAAAAAA
AAAAAAAAAA AAA
Product
| Product | sps2 |
| Description | selenophosphate synthetase 2 (SPS2), catalyzes formation of selenophosphate - selenium donor in biosyntheses of Sec on tRNA. |
| Modifications | 316..318,aa:Sec |
MAEASATGAC GEAMAAAEGS SGPAGLTLGR SFSNYRPFEP QALGLSPSWR LTGFSGMKGU GCKVPQEALL
KLLAGLTRPD VRPPLGRGLV GGQEEASQEA GLPAGAGPSP TFPALGIGMD SCVIPLRHGG LSLVQTTDFF
YPLVEDPYMM GRIACANVLS DLYAMGITEC DNMLMLLSVS QSMSEEEREK VTPLMVKGFR DAAEEGGTAV
TGGQTVVNPW IIIGGVATVV CQPNEFIMPD SAVVGDVLVL TKPLGTQVAV NAHQWLDNPE RWNKVKMVVS
REEVELAYQE AMFNMATLNR TAAGLMHTFN AHAATDITGF GILGHSQNLA KQQRNEVSFV IHNLPIIAKM
AAVSKASGRF GLLQGTSAET SGGLLICLPR EQAARFCSEI KSSKYGEGHQ AWIVGIVEKG NRTARIIDKP
RVIEVLPRGA TAAVLAPDSS NASSEPSS
Publications
- Grundner-Culemann E, Martin GW, Harney JW, Berry MJ. (1999) Two distinct SECIS structures capable of directing selenocysteine incorporation in eukaryotes. RNA. 5(5):625-635. [abstract]
- Fagegaltier D, Lescure A, Walczak R, Carbon P, Krol A. (2000) Structural analysis of new local features in SECIS RNA hairpins. Nucleic Acids Res. 28(14):2679-2689. [abstract]
- Guimarães MJ, Peterson D, Vicari A, Cocks BG, Copeland NG, Gilbert DJ, Jenkins NA, Ferrick DA, Kastelein RA, Bazan JF, Zlotnik A. (1996) Identification of a novel selD homolog from eukaryotes, bacteria, and archaea: is there an autoregulatory mechanism in selenocysteine metabolism?. Proc Natl Acad Sci U S A. 93(26):15086-15091. [abstract]